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<h1 id="firstHeading" class="firstHeading mw-first-heading"><span class="mw-page-title-main">Solanidin</span></h1>
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<div id="mw-content-text" class="mw-body-content mw-content-ltr" lang="de" dir="ltr"><div class="mw-content-ltr mw-parser-output" lang="de" dir="ltr"><table class="wikitable infobox float-right" id="Vorlage_Infobox_Chemikalie" style="font-size:90%; margin-top:0; width:350px;" summary="Infobox Chemikalie">
<tbody><tr>
<th colspan="2" style="background:#FFDEAD; color:#202122;">Strukturformel
</th></tr>
<tr>
<td colspan="2" class="hintergrundfarbe-basis skin-invert-image" style="text-align:center;"><span typeof="mw:File"></span>
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<tr>
<th colspan="2" style="background:#FFDEAD; color:#202122;">Allgemeines
</th></tr>
<tr>
<td style="width:33%;">Name
</td>
<td>Solanidin
</td></tr>
<tr>
<td>Andere Namen
</td>
<td>
<p>(3β)-Solanid-5-en-3-ol (<a href="IUPAC-Nomenklatur" class="mw-redirect" title="IUPAC-Nomenklatur">IUPAC</a>)
</p>
</td></tr>
<tr>
<td><a href="Summenformel" title="Summenformel">Summenformel</a>
</td>
<td>C<sub>27</sub>H<sub>43</sub>NO
</td></tr>
<tr>
<td>Kurzbeschreibung
</td>
<td>
<p>weißer, kristalliner Feststoff<sup id="cite_ref-Sigma_1-0" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
</p>
</td></tr>
<tr>
<th colspan="2" style="background:#FFDEAD; color:#202122;">Externe Identifikatoren/Datenbanken
</th></tr>
<tr>
<td colspan="2" style="padding:0;">
<table class="mw-collapsible mw-collapsed wikitable" data-expandtext="+" data-collapsetext="−" style="border-top:none; margin:-1px; width:calc(100% + 2px);">
<tbody><tr>
<td style="width:33%;"><a href="CAS-Nummer" title="CAS-Nummer">CAS-Nummer</a>
</td>
<td><span title="Untervorlage eingebunden: CASRN"></span><a rel="nofollow" class="external text" href="https://commonchemistry.cas.org/detail?cas_rn=80-78-4">80-78-4</a><span class="editoronly" style="display:none;"></span>
</td>
<td style="background:#FFDEAD; color:#202122; border-top:1px solid #FFDEAD; padding:0.2em 0; vertical-align:bottom; width:5%;">
</td></tr>
<tr>
<td><a href="EG-Nummer" title="EG-Nummer">EG-Nummer</a>
</td>
<td colspan="2">201-309-5
</td></tr>
<tr>
<td><a href="Europ%C3%A4ische_Chemikalienagentur" title="Europäische Chemikalienagentur">ECHA</a>-InfoCard
</td>
<td colspan="2"><a rel="nofollow" class="external text" href="https://www.echa.europa.eu/de/substance-information/-/substanceinfo/100.001.191">100.001.191</a>
</td></tr>
<tr>
<td><a href="PubChem" title="PubChem">PubChem</a>
</td>
<td colspan="2"><a rel="nofollow" class="external text" href="https://pubchem.ncbi.nlm.nih.gov/compound/65727">65727</a>
</td></tr>
<tr>
<td><a href="ChemSpider" title="ChemSpider">ChemSpider</a>
</td>
<td colspan="2"><a rel="nofollow" class="external text" href="https://www.chemspider.com/Chemical-Structure.59150.html">59150</a>
</td></tr>
<tr>
<td style="border-right:1px solid #a2a9b1;"><a href="Wikidata" title="Wikidata">Wikidata</a>
</td>
<td colspan="2"><a href="https://www.wikidata.org/wiki/Q3489153" class="extiw external" title="d:Q3489153">Q3489153</a>
</td></tr></tbody></table>
</td></tr>
<tr>
<th colspan="2" style="background:#FFDEAD; color:#202122;">Eigenschaften
</th></tr>
<tr>
<td><a href="Molare_Masse" title="Molare Masse">Molare Masse</a>
</td>
<td>397,65 g·<a href="Mol" title="Mol">mol</a><sup>−1</sup>
</td></tr>
<tr>
<td><a href="Aggregatzustand" title="Aggregatzustand">Aggregatzustand</a>
</td>
<td>
<p>fest<sup id="cite_ref-Sigma_1-1" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
</p>
</td></tr>
<tr>
<td><a href="Schmelzpunkt" title="Schmelzpunkt">Schmelzpunkt</a>
</td>
<td>
<p>210–218 °C<sup id="cite_ref-Sigma_1-2" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
</p>
</td></tr>
<tr>
<td><a href="Siedepunkt" title="Siedepunkt">Siedepunkt</a>
</td>
<td>
<p>503 °C<sup id="cite_ref-Sigma_1-3" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
</p>
</td></tr>
<tr>
<th colspan="2" style="background:#FFDEAD; color:#202122;">Sicherheitshinweise
</th></tr>
<tr>
<td colspan="2">
<table cellspacing="0" cellpadding="2" style="width:100%;">
<tbody><tr>
<td colspan="2" style="text-align:center"><b><a href="Global_harmonisiertes_System_zur_Einstufung_und_Kennzeichnung_von_Chemikalien" title="Global harmonisiertes System zur Einstufung und Kennzeichnung von Chemikalien">GHS-Gefahrstoffkennzeichnung</a></b><sup id="cite_ref-Sigma_1-4" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
<table class="hintergrundfarbe-neutral" style="text-align:center; margin-left:auto; margin-right:auto; display:flex; justify-content:center;">
<tbody><tr>
<td><span typeof="mw:File"><a href="Global_harmonisiertes_System_zur_Einstufung_und_Kennzeichnung_von_Chemikalien#Übersicht:_EU-Gefahrensymbole,_UN/GHS-Gefahrenpiktogramme,_UN/ADR-Gefahrensymbole" title="07 – Achtung"></a></span>
</td>
<td><span typeof="mw:File"><a href="Global_harmonisiertes_System_zur_Einstufung_und_Kennzeichnung_von_Chemikalien#Übersicht:_EU-Gefahrensymbole,_UN/GHS-Gefahrenpiktogramme,_UN/ADR-Gefahrensymbole" title="08 – Gesundheitsgefährdend"></a></span>
</td></tr></tbody></table>
<p><b>Achtung</b>
</p>
</td></tr>
<tr>
<td rowspan="2" width="33%" style="border-top:1px #A7A7A7 dashed; border-right:1px #A7A7A7 dashed;"><a href="H-_und_P-S%C3%A4tze" title="H- und P-Sätze">H- und P-Sätze</a>
</td>
<td style="border-top:1px #A7A7A7 dashed;">H: <span title="Untervorlage eingebunden: H-Sätze"></span><a href="H-_und_P-S%C3%A4tze#H-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Gesundheitsschädlich bei Verschlucken.">302</span></span></a>‐<a href="H-_und_P-S%C3%A4tze#H-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Kann vermutlich das Kind im Mutterleib schädigen.">361d</span></span></a>‐<a href="H-_und_P-S%C3%A4tze#H-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Kann für Wasserorganismen schädlich sein, mit langfristiger Wirkung.">413</span></span></a>
</td></tr>
<tr>
<td style="border-top:1px #A7A7A7 dashed;">P: <span title="Untervorlage eingebunden: P-Sätze"></span><a href="H-_und_P-S%C3%A4tze#P-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Vor Gebrauch alle Sicherheitshinweise lesen und verstehen.">202</span></span></a>‐<a href="H-_und_P-S%C3%A4tze#P-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Nach Gebrauch … gründlich waschen.
(Die vom Gesetzgeber offen gelassene Einfügung ist vom Inverkehrbringer zu ergänzen)">264</span></span></a>‐<a href="H-_und_P-S%C3%A4tze#P-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Bei Gebrauch nicht essen, trinken oder rauchen.">270</span></span></a>‐<a href="H-_und_P-S%C3%A4tze#P-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Freisetzung in die Umwelt vermeiden.">273</span></span></a>‐<a href="H-_und_P-S%C3%A4tze#P-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Bei Verschlucken: Bei Unwohlsein Giftinformationszentrum / Arzt / … anrufen.">301+312</span></span></a>‐<a href="H-_und_P-S%C3%A4tze#P-Sätze" title="H- und P-Sätze"><span style="display:inline-block;"><span style="color:#ff5400; border-bottom:1px dotted #ff5400;" title="Bei Exposition oder falls betroffen: Ärztlichen Rat Einholen / ärztliche Hilfe hinzuziehen.">308+313</span></span></a><sup id="cite_ref-Sigma_1-5" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup>
</td></tr>
</tbody></table>
</td></tr>
<tr>
<td><a href="Toxizit%C3%A4t" title="Toxizität">Toxikologische Daten</a>
</td>
<td>
<p>590 mg·kg<sup>−1</sup> (<a href="Letale_Dosis" title="Letale Dosis">LD<sub>50</sub></a>, <a href="Ratten" title="Ratten">Ratte</a>, <a href="Peroral" title="Peroral">oral</a>)<sup id="cite_ref-Sigma_1-6" class="reference"><a href="#cite_note-Sigma-1"><span class="cite-bracket">[</span>1<span class="cite-bracket">]</span></a></sup><span class="editoronly" style="display:none;"></span>
</p>
</td></tr>
<tr>
<td colspan="2" style="background:#FFDEAD; color:#202122; font-size:80%; text-align:center; line-height:150%; padding:.25em;">Wenn nicht anders vermerkt, gelten die angegebenen Daten bei <a href="Standardbedingungen" title="Standardbedingungen">Standardbedingungen</a> (0 °C, 1000 hPa).
</td></tr></tbody></table><p><span class="editoronly" style="display:none;"></span>
</p><p><b>Solanidin</b> ist ein <a href="Steroidalkaloide" title="Steroidalkaloide">Steroidalkaloid</a>.
</p>
<div class="mw-heading mw-heading2"><h2 id="Vorkommen">Vorkommen</h2></div>
<p>Solanidin ist Bestandteil der beiden <a href="Glycoalkaloide" class="mw-redirect" title="Glycoalkaloide">Glycoalkaloide</a> <a href="Solanin" title="Solanin">Solanin</a> (mit der Zuckerkomponente <a href="Solatriose" title="Solatriose">Solatriose</a>) und <a href="Chaconin" title="Chaconin">Chaconin</a> (mit der Zuckerkomponente Chacotriose), die in der <a href="Kartoffel" title="Kartoffel">Kartoffel</a> vorkommen.<sup id="cite_ref-:0_2-0" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup><sup id="cite_ref-Römpp_3-0" class="reference"><a href="#cite_note-Römpp-3"><span class="cite-bracket">[</span>3<span class="cite-bracket">]</span></a></sup>
</p>
<div class="mw-heading mw-heading2"><h2 id="Synthese">Synthese</h2></div>
<p>Solanidin kann ausgehend von acetyliertem <a href="Diosgenin" title="Diosgenin">Diosgenin</a> in acht Stufen gewonnen werden.<sup id="cite_ref-4" class="reference"><a href="#cite_note-4"><span class="cite-bracket">[</span>4<span class="cite-bracket">]</span></a></sup>
</p>
<div class="mw-heading mw-heading2"><h2 id="Eigenschaften">Eigenschaften</h2></div>
<p>Solanidin ist giftig. In einer Studie an <a href="Hausmaus" title="Hausmaus">Mäusen</a> hat es zu einer Vergrößerung der <a href="Leber" title="Leber">Leber</a> geführt sowie bei schwangeren Tieren zu Fehlgeburten.<sup id="cite_ref-:0_2-1" class="reference"><a href="#cite_note-:0-2"><span class="cite-bracket">[</span>2<span class="cite-bracket">]</span></a></sup> Die <a href="Teratogen" title="Teratogen">teratogene</a> Wirkung ist aber deutlich geringer als bei den Glycosiden Solanin und Chaconin.<sup id="cite_ref-5" class="reference"><a href="#cite_note-5"><span class="cite-bracket">[</span>5<span class="cite-bracket">]</span></a></sup>
</p><p>In einer Studie <i><a href="In_silico" title="In silico">in silico</a></i> zeigte Solanidin <a href="Antivirale_Medikamente" class="mw-redirect" title="Antivirale Medikamente">antivirale</a> Eigenschaften gegen <a href="SARS-CoV-2" title="SARS-CoV-2">SARS-CoV-2</a>.<sup id="cite_ref-6" class="reference"><a href="#cite_note-6"><span class="cite-bracket">[</span>6<span class="cite-bracket">]</span></a></sup>
</p>
<div class="mw-heading mw-heading2"><h2 id="Verwendung">Verwendung</h2></div>
<p>Solanidin eignet sich als <a href="Biomarker_(Medizin)" title="Biomarker (Medizin)">Biomarker</a>, um Genvarianten von <a href="Cytochrom_P450_2D6" title="Cytochrom P450 2D6">Cytochrom P450 2D6</a> zu erkennen, welche eine wichtige Rolle bei der <a href="Metabolisierung" class="mw-redirect" title="Metabolisierung">Metabolisierung</a> von Medikamenten spielen.<sup id="cite_ref-7" class="reference"><a href="#cite_note-7"><span class="cite-bracket">[</span>7<span class="cite-bracket">]</span></a></sup>
</p>
<div class="mw-heading mw-heading2"><h2 id="Einzelnachweise">Einzelnachweise</h2></div>
<ol class="references">
<li id="cite_note-Sigma-1"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-Sigma_1-0">a</a></sup> <sup><a href="#cite_ref-Sigma_1-1">b</a></sup> <sup><a href="#cite_ref-Sigma_1-2">c</a></sup> <sup><a href="#cite_ref-Sigma_1-3">d</a></sup> <sup><a href="#cite_ref-Sigma_1-4">e</a></sup> <sup><a href="#cite_ref-Sigma_1-5">f</a></sup> <sup><a href="#cite_ref-Sigma_1-6">g</a></sup></span> <span class="reference-text">Datenblatt <span style="font-style:italic;"><a rel="nofollow" class="external text" href="https://www.sigmaaldrich.com/catalog/product/SIGMA/13264">Solanidin, ≥97.0%</a></span> bei <a href="Sigma-Aldrich" title="Sigma-Aldrich">Sigma-Aldrich</a>, abgerufen am 28. Juli 2023 (<a rel="nofollow" class="external text" href="https://www.sigmaaldrich.com/DE/de/sds/SIGMA/13264?userType=anonymous">PDF</a>).<span class="editoronly" style="display:none;"></span></span>
</li>
<li id="cite_note-:0-2"><span class="mw-cite-backlink">↑ <sup><a href="#cite_ref-:0_2-0">a</a></sup> <sup><a href="#cite_ref-:0_2-1">b</a></sup></span> <span class="reference-text">Mendel Friedman, P.R. Henika, B.E. Mackey: <cite style="font-style:italic">Effect of feeding solanidine, solasodine and tomatidine to non-pregnant and pregnant mice</cite>. In: <cite style="font-style:italic"><a href="Food_and_Chemical_Toxicology" title="Food and Chemical Toxicology">Food and Chemical Toxicology</a></cite>. <span style="white-space:nowrap">Band<span style="display:inline-block;width:.2em"> </span>41</span>, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>1</span>, Januar 2003, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>61–71</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1016/S0278-6915%2802%2900205-3">10.1016/S0278-6915(02)00205-3</a></span>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:Solanidin&rft.atitle=Effect+of+feeding+solanidine%2C+solasodine+and+tomatidine+to+non-pregnant+and+pregnant+mice&rft.au=Mendel+Friedman%2C+P.R.+Henika%2C+B.E.+Mackey&rft.date=2003-01&rft.doi=10.1016%2FS0278-6915%2802%2900205-3&rft.genre=journal&rft.issue=1&rft.jtitle=Food+and+Chemical+Toxicology&rft.pages=61-71&rft.volume=41" style="display:none"> </span></span>
</li>
<li id="cite_note-Römpp-3"><span class="mw-cite-backlink"><a href="#cite_ref-Römpp_3-0">↑</a></span> <span class="reference-text">Eintrag zu <a rel="nofollow" class="external text" href="https://roempp.thieme.de/lexicon/RD-19-02870"><i>Solanum-Steroidalkaloidglycoside</i></a>. In: <i><a href="R%C3%B6mpp_Online" class="mw-redirect" title="Römpp Online">Römpp Online</a>.</i> Georg Thieme Verlag, abgerufen am 28. Juli 2023.<span class="editoronly" style="display:none;"></span></span>
</li>
<li id="cite_note-4"><span class="mw-cite-backlink"><a href="#cite_ref-4">↑</a></span> <span class="reference-text">Zhi-Dan Zhang, Yong Shi, Jing-Jing Wu, Jing-Rong Lin, Wei-Sheng Tian: <cite style="font-style:italic">Synthesis of Demissidine and Solanidine</cite>. In: <cite style="font-style:italic"><a href="Organic_Letters" title="Organic Letters">Organic Letters</a></cite>. <span style="white-space:nowrap">Band<span style="display:inline-block;width:.2em"> </span>18</span>, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>12</span>, 17. Juni 2016, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>3038–3040</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1021/acs.orglett.6b01320">10.1021/acs.orglett.6b01320</a></span>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:Solanidin&rft.atitle=Synthesis+of+Demissidine+and+Solanidine&rft.au=Zhi-Dan+Zhang%2C+Yong+Shi%2C+Jing-Jing+Wu%2C+...&rft.date=2016-06-17&rft.doi=10.1021%2Facs.orglett.6b01320&rft.genre=journal&rft.issue=12&rft.jtitle=Organic+Letters&rft.pages=3038-3040&rft.volume=18" style="display:none"> </span></span>
</li>
<li id="cite_note-5"><span class="mw-cite-backlink"><a href="#cite_ref-5">↑</a></span> <span class="reference-text">Mendel. Friedman, J. R. Rayburn, J. A. Bantle: <cite style="font-style:italic">Structural relationships and development toxicity of Solanum alkaloids in the frog embryo teratogenesis assay-Xenopus</cite>. In: <cite style="font-style:italic"><a href="Journal_of_Agricultural_and_Food_Chemistry" title="Journal of Agricultural and Food Chemistry">Journal of Agricultural and Food Chemistry</a></cite>. <span style="white-space:nowrap">Band<span style="display:inline-block;width:.2em"> </span>40</span>, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>9</span>, September 1992, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>1617–1624</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1021/jf00021a029">10.1021/jf00021a029</a></span>.<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:Solanidin&rft.atitle=Structural+relationships+and+development+toxicity+of+Solanum+alkaloids+in+the+frog+embryo+teratogenesis+assay-Xenopus&rft.au=Mendel.+Friedman%2C+J.+R.+Rayburn%2C+J.+A.+Bantle&rft.date=1992-09&rft.doi=10.1021%2Fjf00021a029&rft.genre=journal&rft.issue=9&rft.jtitle=Journal+of+Agricultural+and+Food+Chemistry&rft.pages=1617-1624&rft.volume=40" style="display:none"> </span></span>
</li>
<li id="cite_note-6"><span class="mw-cite-backlink"><a href="#cite_ref-6">↑</a></span> <span class="reference-text">Julien A. Delbrouck, Michael Desgagné, Christian Comeau, Kamal Bouarab, François Malouin, Pierre-Luc Boudreault: <cite style="font-style:italic">The Therapeutic Value of Solanum Steroidal (Glyco)Alkaloids: A 10-Year Comprehensive Review</cite>. In: <cite style="font-style:italic"><a href="Molecules" title="Molecules">Molecules</a></cite>. <span style="white-space:nowrap">Band<span style="display:inline-block;width:.2em"> </span>28</span>, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>13</span>, 23. Juni 2023, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>4957</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.3390/molecules28134957">10.3390/molecules28134957</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/37446619?dopt=Abstract">PMID 37446619</a>, <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343844/">PMC 10343844</a> (freier Volltext).<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:Solanidin&rft.atitle=The+Therapeutic+Value+of+Solanum+Steroidal+%28Glyco%29Alkaloids%3A+A+10-Year+Comprehensive+Review&rft.au=Julien+A.+Delbrouck%2C+Michael+Desgagn%C3%A9%2C+Christian+Comeau%2C+...&rft.date=2023-06-23&rft.doi=10.3390%2Fmolecules28134957&rft.genre=journal&rft.issue=13&rft.jtitle=Molecules&rft.pages=4957&rft.pmc=10343844&rft.pmid=37446619&rft.volume=28" style="display:none"> </span></span>
</li>
<li id="cite_note-7"><span class="mw-cite-backlink"><a href="#cite_ref-7">↑</a></span> <span class="reference-text">Birgit M. Wollmann, Elisabet Størset, Marianne Kristiansen Kringen, Espen Molden, Robert L. Smith: <cite style="font-style:italic">Prediction of CYP2D6 poor metabolizers by measurements of solanidine and metabolites—a study in 839 patients with known CYP2D6 genotype</cite>. In: <cite style="font-style:italic"><a href="European_Journal_of_Clinical_Pharmacology" title="European Journal of Clinical Pharmacology">European Journal of Clinical Pharmacology</a></cite>. <span style="white-space:nowrap">Band<span style="display:inline-block;width:.2em"> </span>79</span>, <span style="white-space:nowrap">Nr.<span style="display:inline-block;width:.2em"> </span>4</span>, April 2023, <span style="white-space:nowrap">S.<span style="display:inline-block;width:.2em"> </span>523–531</span>, <a href="Digital_Object_Identifier" title="Digital Object Identifier">doi</a>:<span class="uri-handle" style="white-space:nowrap"><a rel="nofollow" class="external text" href="https://doi.org/10.1007/s00228-023-03462-y">10.1007/s00228-023-03462-y</a></span>, <a class="external mw-magiclink-pmid" rel="nofollow" href="https://www.ncbi.nlm.nih.gov/pubmed/36806969?dopt=Abstract">PMID 36806969</a>, <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10038974/">PMC 10038974</a> (freier Volltext).<span class="Z3988" title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rfr_id=info:sid/de.wikipedia.org:Solanidin&rft.atitle=Prediction+of+CYP2D6+poor+metabolizers+by+measurements+of+solanidine+and+metabolites%E2%80%94a+study+in+839+patients+with+known+CYP2D6+genotype&rft.au=Birgit+M.+Wollmann%2C+Elisabet+St%C3%B8rset%2C+Marianne+Kristiansen+Kringen%2C+...&rft.date=2023-04&rft.doi=10.1007%2Fs00228-023-03462-y&rft.genre=journal&rft.issue=4&rft.jtitle=European+Journal+of+Clinical+Pharmacology&rft.pages=523-531&rft.pmc=10038974&rft.pmid=36806969&rft.volume=79" style="display:none"> </span></span>
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